The COVID-19 Pandemic in Ethiopia

A prospective observational cohort study designed to understand the characteristics and outcomes of the profile of Hospitalized African COVID-19 patients


Keywords: COVID-19; time to clinical improvement; prospective cohort, survival analysis; Cox PH model; logistic regression model; Ethiopia

Results

Images of some of the results obtained

Foto
Flow chart showing the disposition of study participants in the final analysis

Description of the Study:

  • Title: Characteristics and outcome profile of Hospitalized African COVID-19 patients: The Ethiopian Context.
  • Principal Investigator: Tigist Workneh Leulseged.
  • Co-investigators: Ishmael S. Hassen, Endalkachew H. Maru, Wuletaw C. Zewde, Negat W. Chamsew, Abdi B. Bayisa, Daniel S. Abebe, Birhanu T. Ayele, Kalkidan T. Yegle, Mesay G. Edo, Eyosyas K. Gurara, Dereje D. Damete, Yared A. Tolera.
  • Center of Implementation: Millennium COVID-19 Care Center, Addis Ababa, Ethiopia.
  • Study Population: 1345 COVID-19 patients, both paediatrics and adults.
  • Study Type: Prospective Observational Cohort.
  • Design: Prospective Cohort.
  • Method: Frequency tables, KM plots, median survival times and Log-rank test were used to describe the data and compare survival distribution between groups. Cox proportional hazard survival model was used to identify determinants of time to clinical improvement and the independent variables and binary logistic regression model was used to assess the presence of a statistically significant association between disease outcome and the independent variables.

Objectives of the Study:

Principal Objective: To assess the characteristics and outcome of COVID-19 patients and to identify determinants of the disease outcome among patients admitted to Millennium COVID-19 Care Center in Ethiopia.

More about this Study:

Context: The COVID-19 pandemic seems to have a different picture in Africa; the first case was identified in the continent after it has already caused a significant loss to the rest of the world and the reported number of cases and mortality rate has been low. Therefore, understanding the characteristics and outcome profile of African COVID-19 patients as this study aims, is crucial.


Added value: Understanding the disease characteristics and outcome in the local context to provide a targeted intervention.

St Pauls Hospital Millennium Medical College leads this study about the profile of Hospitalized African COVID-19 patients.

Other Epidemiological Studies:

Flower 729514 1920

E-speranza-COVID19 Project

This study aims to demonstrate efficacy of Montelukast for patients with persistent COVID-19 to help them improve their quality of life.

CIBERESUCI COVID

CIBERES UCI COVID is a fundamental study that will improve care of critical patients infected by COVID-19.

ANTICOV Study : COVID-19 en Afrique

Collaborez avec l’étude ANTICOV et contribuez à traiter la COVID-19 en Afrique.

Antibiotic prescription during the COVID-19 pandemic

Antimicrobial stewardship approaches urgently need to be reinforced during the COVID-19 pandemic. This study evaluates the impact of the COVID-19 on antibiotic consumption.

Influenza Vaccination, ACEI and ARB in the Evolution of COVID-19

A study to determine if influenza vaccination or ACEI or ARB medication has effects on COVID-19.

Progestérone pour traiter le COVID-19

Est-ce que les hormones sexuelles peuvent aider les hommes survivre le COVID-19 ? Cette étude a pour objectif évaluer la sécurité et l’efficacité de la progestérone dans le traitement de COVID-19 chez les hommes hospitalisés.

PanCOVID19: Evaluating Pharmacological Treatments

Open, randomized, adaptive, phase III clinical trial study to evaluate the efficacy of various pharmacological alternatives in the treatment of severe infection in COVID-19 pediatric patients.

MMR Vaccine and the Immune Response to SARS-CoV-2

Is the MMR vaccine involved in the immune response to SARS-CoV-2? This study aims to answer that question by investigating the effect of the MMR vaccine on COVID-19.

AstraZeneca Study of COVID-19 Vaccine Candidate AZD1222

Clinical trial designed to determine if the vaccine candidate, AZD1222, can prevent symptomatic COVID-19.

Amantadine and COVID-19

Participate in this study and help us discover the role of Amantadine as a therapeutic alternative to fight COVID-19.