COVID-19 and Pregnancy

What is the impact of COVID-19 in mothers and fetuses? This study aims to answer this question through an online survey to pregnant women with and without COVID-19

Description of the Study:

  • Title: COVID19 and pregnancy: social online survey to assess clinical spectrum and impact on maternal-fetal wellbeing.
  • Principal Investigator: Eduard Gratacós.
  • Centres of Implementation: Sant Joan De Déu Children’s Hospital (SJD), Hospital Clinic Barcelona (HCB), Hospital Sant Pau Barcelona, Hospital Italiano de Buenos Aires, Hospital Universitario de Chile, ESE Clinica Maternidad Rafael Calvo, Żelazna Medical Center and Institute of Clinical Sciences Lund.
  • Study Population: 10,000 pregnant women, with and without COVID-19.
  • Design: A short and realistic survey will be conducted using a structured questionnaire that can be completed in only 5-10′. Despite the short time required, it will provide valuable information on disease presentation, pregnancy course and anxiety level through validated questionnaires. In addition, geolocation and the available large databases of socio-economic and air pollution maps will be used to model these factors using artificial intelligence approaches.

Objectives of the Study:

Principal Objectives:
(1) To describe the prevalence of SARS-CoV-2 infection in pregnant women in different countries and regions of the world.
(2) To describe the clinical spectrum and the impact on perinatal outcomes at different moments of gestation.
(3) To evaluate geographical or health system factors associated with the clinical presentation and the rate of severe complications.
(4) To evaluate factors associated with infection and clinical presentation, including stress.

More about this Study:

Scientific Context: Despite most pregnancies with COVID-19 have a mild disease, there are reports of cases with severe or even fatal presentations, which create alarm among women, doctors and the society.

Likewise, pregnant women are highly vulnerable to the « collateral damage » of COVID-19, i.e. the long term social, wellbeing and economic consequences. Because they are young, and apparently « more protected » from COVID-19, there has been a lack of attention on pregnancy. This has led to lack of reliable scientific data, generating stress on women and preventing evidence-based information to inform the society, make recommendations and guide policies. Therefore, there is an urgent need to have solid data on how COVID19 affects pregnancy and their child.

International collaboration is critical need to accelerate generation of knowledge.

Sant Joan de Déu: It is a university hospital specializing in the fields of pediatrics, gynecology, and obstetrics, which has a long history of more than 150 years, during which it has undergone many transformations and changes due to the need to adapt both to the social and health conditions of the time and to technological advances and the evolution of health care.

Sant Joan Compressio

Other Studies about Obstetrics:


MOOD-COVID aims to study the impact of the pandemic on the mental health of pregnant women, young mothers and their children.


This multinational study shows that women with COVID are 50% more likely to have complications during pregnancy, but if COVID is asymptomatic the risk is the same as if they did not have the infection.

LacCOVID Study

The LacCOVID study has shown that milk from lactating women who have been vaccinated with Pfizer-BioNTech contains specific antibodies against the SARS-CoV-2 coronavirus.

SARS-CoV-2 Infection During Pregnancy

This international study aims to determine the clinical spectrum and the impact of SARS-CoV-2 infection during pregnancy.

Breast Milk and Vertical Transmission of SARS-CoV-2

Should breastfeeding women take care of the vertical transmission of SARS-CoV-2? Let’s study the role of COVID-19 in lactation.


This study allows in-depth understanding of the transmission of the infection, as well as the immune response that occurs in pregnant mothers and the newborn population during COVID-19.

Preventing SARS-CoV-2 Infection During Pregnancy

Can hydroxychloroquine (HCQ) safely prevent infection and severe complications in pregnant women? This study focues on prevent COVID-19 during pregnancy.