Vaccination In People With Long COVID

This study aims to determine the effects of vaccination against SARS-CoV-2 in people with long COVID

The Sociedad Española de Médicos Generales y de Familia (SEMG) and the collective of affected people @longcovidACTS have been working together for months to try to provide answers to those affected by Persistent or Long COVID.

Now they want to go a step further and want to know what the situation is regarding vaccination against SARS-CoV-2 when suffering from Persistent COVID or Long COVID.

Description of the Study:

  • Title: Study of the effects of vaccination in people with persistent COVID.
  • Principal Investigators: Sociedad Española de Médicos Generales y de Familia (SEMG) and the LONG COVID ACTS alliance of regional groups.
  • Study Population: Individuals who:
    – Have persistent COVID or Long COVID, i.e. they have had COVID-19 and their symptoms persist beyond 4 weeks, and in addition.
    – Have had two doses of SARS-CoV-2 vaccine, or have had one dose and are not going to have a second dose.
  • Study Type: Observational study.
  • Design: A survey will identify how the vaccine affects their symptomatology, i.e. which patients with persistent COVID could benefit from vaccination and which could not, or whether the effect varies with the type of vaccine administered.
  • Methods: Anonymised form, which takes about five minutes to complete and does not require any personal identification data, for the collection of information in relation to COVID-19 vaccination.

Objectives of the Study:

Principal Objective: To follow up the effect of vaccination against SARS-CoV-2 in patients who have had COVID-19 and their symptoms persist over time beyond 4 weeks, i.e. patients with persistence of COVID-19 symptoms.

More about this Study:

Scientific Context: The increase in COVID-19 infections has made the existence of so-called persistent COVID-19 or “long COVID-19” increasingly evident. This is the name given to cases where the infected patient has symptoms beyond the approximately 14 days that are considered normal for COVID-19 cases. Although sometimes referred to as sequelae, these are actually symptoms: patients with persistent COVID-19 may experience symptoms four weeks or even months after infection. Symptoms may include coughing, hair loss, fatigue or chest pain.


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CIBERES UCI COVID is a fundamental study that will improve care of critical patients infected by COVID-19.


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