Clinical Characterization of Patients With COVID-19 in Primary Care

This retrospective observational study aims to clinically characterise patients with COVID-19 in Primary Care in Catalonia

Keywords: COVID-19; Spain; angiotensin II type 2 receptor blockers; angiotensin-converting enzyme inhibitors; characteristic; mortality; observational; primary health care; retrospective; risk; risk factors


(1) 6.84% of the population studied were diagnosed with COVID-19 during the study period, and the most common clinical conditions of these patients were:
– hypertension (22.1%)
– obesity (21.7%)

(2) 0.77% of the patients in the study population died during the study period.

(3) The number of deaths among patients without COVID-19 was 0.56% (mean age 80.6 years, SD 13.3).

(4) The number of deaths of patients diagnosed with COVID-19 was 855/23,844 (3.58%; mean age 83.0 years, SD 10.80) with an OR of 6.58 (95% CI 6.06-7.15).

Description of the Study:

  • Title: Clinical Characterization of Patients With COVID-19 in Primary Care in Catalonia: Retrospective Observational Study
  • Principal Investigators: Miguel Angel Mayer, Josep Vidal-Alaball, Anna Puigdellívol-Sánchez, Francesc X. Marín Gomez, Angela Leis and Jacobo Mendioroz Peña.
  • Study Population: 348,596 patients (aged >15 years) registered in the Primary Care Services Information Technologies System of the Catalan Central Region (50.34% were women).
  • Study Type: Observational retrospective study.
  • Methods: Observational retrospective study of patients diagnosed with COVID-19 in the Catalan Central Region of Spain between March 1 and August 17, 2020. The data were obtained from the Primary Care Services Information Technologies System of the Catalan Institute of Health in Barcelona, Spain.

Objectives of the Study:

Principal Objectives:
(1) Compare the characteristics of patients diagnosed with COVID-19 to those of patients without COVID-19 in primary care.
(2) Determine the risk factors associated with the outcome of mortality.
(3) Determine the potential influence of certain medications, such as ACEIs and ARBs, on the mortality of patients with COVID-19.

More about this Study:

Scientific Context: Spain has one of the highest incidences of COVID-19, with more than 1,000,000 cases as of the end of October 2020. Patients with a history of chronic conditions, obesity, and cancer are at greater risk from COVID-19; moreover, concerns surrounding the use of angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin type II receptor blockers (ARBs) and its relationship to COVID-19 susceptibility have increased since the beginning of the pandemic.

ICS supports this study to clinically characterise patients with COVID-19 in Primary Care in Catalonia.

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