COnV-ert study, convalescent plasma to stop COVID-19

Early administration of convalescent plasma in people over 50 years of age with mild to moderate COVID-19 may slow disease progression and decrease the severity of symptoms

If you meet the following three criteria, you may be eligible for the study. Participate! Help us!

  1. Positive in COVID-19
  2. Age ≥ 50 years
  3. Symptomatic
Dr. Oriol Mitjà, comments on the COnV-ert study aimed at reducing COVID-19 symptoms and disease severity.


If you have any questions, please contact the researchers by calling 634 755 945 or sending an e-mail to

Description of the Study:

  • Title: Plasma for Early Treatment in Non-hospitalised Mild or Moderate COVID-19 Patients.
  • Principal Investigators: Oriol Mitjà and Bonaventura Clotet.
  • Centers of Implementation: Centers in the health region of Bages-Berguedà, Barcelona, Metropolitan South and Metropolitan North. In Catalunya Central, people who meet the requirements will be treated at CUAP Bages and in the Emergency Room of the Hospital Sant Bernabé de Berga.
  • Study Population: People with 50 years of age or older who have had a positive COVID-19 result by PCR or rapid antigen test and who have symptoms not requiring hospitalization for less than 7 days.
  • Study type: Double-blind, Randomized, Prospective Clinical Trial.
  • Design: Randomized study, in which there will be two treatment groups that, in addition to the therapy prescribed by their medical professional for COVID-19, will receive either convalescent plasma or placebo. Assignment to one group or the other will be randomized. It is also a double-blind study in which neither the research team nor the participant will know to which group the latter belongs.
  • Methods: The two treatments (convalescent plasma and placebo) will be administered by intravenous infusion of about 30-40 minutes of duration in a hospital setting. Administration will be performed on the first day of the study, after checking blood group compatibility.

Objectives of the Study:

Principal Objective: To evaluate the efficacy and safety of convalescent plasma treatment in people over 50 years of age with mild to moderate COVID-19 disease who are not hospitalized.

More about this Study:

Scientific context: Coronavirus disease 2019 (COVID-19) is a respiratory infection caused by the SARS-CoV-2 virus. The uncontrolled spread of the SARS-CoV-2 coronavirus has generated an unprecedented health emergency that requires the urgent development of new strategies to protect the population, mainly those most at risk.

Convalescent plasma is given by persons who have passed COVID-19 and contain antibodies against the SARS-CoV-2 virus.

Plasma therapy has been used to treat many conditions and is safe. Convalescent plasma therapy could be very useful for the entire population, mainly for those who are older or have risk factors for developing complications of COVID-19.

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