COVICAT Study

The COVICAT study aims to evaluate the evolution of the incidence of SARS-CoV-2 coronavirus infection in the Catalan population over a 12-month period


Description of the Study:

  • Title: COVICAT.
  • Principal Investigator: Manolis Kogevinas.
  • Co-investigators: Lourdes Arjona, Gemma Castaño, Anna Delgado, Carlota Dobaño, Ana Espinosa and Judith Garcia.
  • Centres Involved: It is a collaboration between the GCAT-Genomes for Life project of the Germans Trias i Pujol Research Institute (IGTP) and two research groups from ISGlobal, a centre promoted by the “la Caixa” Foundation, and the Hospital Clínic de Barcelona.
  • Study Population: 24,000 volunteers from different population cohorts, covering a broad spectrum of the adult population (GCAT-Genomes for life and MCC-Spain) and other population groups with special characteristics: cohort of mothers and adolescents (INMA Sabadell), at-risk population with respiratory diseases (ECHRS and Urban Training) or agricultural workers (LeRAgs).
  • Study Type: prospective epidemiological study of population-based cohorts.
  • Methods:
    – Participants are asked to answer an online questionnaire with questions about lifestyle habits and the impact the virus has had on them and their environment.
    – In addition, to complete the study, participants must voluntarily provide a blood sample. These will be used for a serological analysis to find out about infections and whether they have immunity to the SARS-CoV-2 virus.
    – Finally, over the next 12 months, participants will be contacted 3 more times to complete a short online follow-up questionnaire to update us on any changes related to symptoms and COVID-19 disease.

Objectives of the Study:

Principal Objectives:
(1) To assess over 12 months the prevalence and incidence of coronavirus (SARS-CoV-2) infection and COVID-19 symptoms in the Catalan population in a sero-epidemiological study of existing population cohorts using high-throughput multiplex serological techniques.
(2) Evaluate over 12 months in repeated contacts the evolution of immunological patterns to estimate the duration of immunity using valid serological techniques.
(3) Prospectively examine environmental, climatic and lifestyle factors associated with SARS-Cov-2 infection and immunity, with COVID-19 disease and prognosis and use of health services.
(4) Assess the multiple effects of confinement on the general population, susceptible groups and the working population, including mental health, social and economic factors, lifestyle, urban living factors, and employment and quality of work.

More about this Study:

Added Value: “What makes this study different is that all the participants are included in population-based cohorts, i.e. we have available pre-pandemic information on each one: their genetic data, clinical history, lifestyle … which gives us a key added value in this epidemiological study,” explains Rafa de Cid, scientific director of the GCAT, one of the cohorts included, which contributes 20,000 of the total number of individuals studied.

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