Col-VID Study: Effectiveness Of Colchicine In Patients With COVID-19

The Col-VID study aims to determine whether the use of colchicine reduces the severity or even prevents death in patients with COVID-19

Description of the Study:

  • Title: Col-VID study.
  • Principal Investigator: Alberto Cecconi.
  • Centres of Implementation: The study stems from the collaboration of the Cardiology, Internal Medicine, Pneumology, Immunology and Clinical Analysis services of the Hospital Universitario de La Princesa. In addition, the Gregorio Marañón and Fundación Jiménez Díaz University Hospitals in Madrid and the Cabueñes University Hospital in Gijón are participating as collaborating centres.
  • Study population: 240 patients hospitalised for coronavirus pneumonia and with hyperinflammation data.

Objectives of the Study:

Principal Objective: To determine whether the use of colchicine, in patients hospitalised for coronavirus pneumonia and with hyperinflammation, reduces the initiation of non-invasive ventilation (CPAP/BiPAP), admission to ICU, initiation of invasive ventilation and even the risk of death.

More about this Study:

Scientific context: Colchicine is an effective and safe anti-inflammatory drug commonly used for the treatment of pericarditis and gout. Considering the inflammation associated with COVID-19 and the mechanism of action of colchicine, this drug could also be helpful in the treatment of patients with coronavirus pneumonia.

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